Development of Biocidical Soaking Agents for Various Textile Goods

Textile materials that are used in medical facilities and other mass gathering locations, employed at the time of epidemics and military engagements are vulnerable to bioburden and may become a source of microbial contamination.

Purpose of the study – to evaluate antimicrobial efficiency of biocidical compositions that are based on quaternary ammonium compounds and guanidine derivative polymers that are used as antimicrobial soaking agents for natural and synthetic textiles.

Materials and methods. The authors have analyzed avalible literature on biocidical additives both in English and Russian languages. The authors also have tested natural and synthetic textiles and different antimicrobial soaking agents (compositions). One-day agar cultures of Staphilococcus aureus (strain 906) and Escherichia coli (strain 1257) served as test microorganisms. The efficiency of antimicrobial soaking agents for textiles towards test microorganisms has been evaluated by “agar plates” and “droplet infection” methods. Biocidical treatment of antimicrobial fabric was considered effective, if the inhibition zone of test microorganisms was at least 4 mm.

Results. The papers under analysis have no data on the possibility of use of such compositions as soaking agents that will permit to obtain antimicrobial fabrics. The experimental studies provided data on bacteriostatic and bactericidal properties of used compositions. The comparative analysis has allowed to determine the most efficient compositions used for soaking of different fabrics.

Conclusions. The soaking that contains 0,05% alkyldimethylbenzylammonium chloride, 0,05% polyhexamethylene guanidine hydrochloride, 0,05% triamin and 40,0% propylene glycol has turned out to be the most efficient one towards gram-positive and gram-negative microorganisms. It gives protective properties both to synthetic (polyamide 100%) and mixed fabrics (cotton 65% and Composition that contains 0,05% katanol and 40,0% polyethyleneglycol may be used to create antimicrobial soaking for fabrics of mixed compositions. This soaking may also be effective towards gram-positive microorganisms.

1. Goyal S, Khot SC, Ramachandran V, Shah KP, Musher DM. Bacterial contamination of medical provides while coast and surgical scrubs: a systematic review. American Journal of Infection Control. 2019;47(8):994–1001. https://doi.org/10.1016/j.ajic.2019.01.012

2. Mishra SK, Maharjan S, Yadav SK, Sah NP, Sharma S, Parajuli K, et al. Bacteria on medical professionals while coast in a university hospital. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020;2020:5957284. https://doi.org/10.1155/2020/5957284

3. Dunn D. Linen: the new frontier in infection control and prevention. AORN Journal. 2022;115:310–324. https://doi.org/10.1002/aorn.13643

4. Cheng VСС, Chen JHK, Leung SSM, So SYC, Wong SCY, et al. Seasonal outbreak of bacillus bacteremia associated with contaminated linen in Hong Kong. Clinical Infectious Diseases. 2017;64(suppl_2):S91–7. https://doi.org/10.1093/cid/cix044

5. Ohl M, Schweizer M, Graham M, Heilmannk K, Boyken L, Diekema D. Hospital privacy curtains are frequently and rapidly contaminated with potentially pathogenic bacteria. American Journal of Infection Control. 2012;40(10):904–6. https://doi.org/10.1016/j.ajic.2011.12.017

6. Shek K, Patidar R, Kohja Z, Liu S, Gawaziuk JP, Gawhtrop M, et al. Rate of contamination of hospital privacy cuntains in a burns/plastic ward: a longitudinal study. American Journal of Infection Control. 2018;46(9):1019–21. https://doi.org/10.1016/j.ajic.2018.03.004

7. Simoncic B, Tomsic B. Structures of Novel Antimicrobial Agents for Textiles – A Review. Textile Research Journal. 2010;80(16):1721–37. https://doi.org/10.1177/0040517510363193

8. Li H, Fernandez A, Pleixats R, Vallribera A. Anti-inflammatory cotton fabrics and silica nanoparticles with potential topical medical application. ACS Applied Materials & Interfacess. 2020;12(23):25658–75.

9. Халиуллина МК, Гадельшина ЭА. Использование различных бактерицидных и фунгицидных добавок в полимерах при производстве антимикробных текстильных материалов. Вестник Казанского технологического университета. 2014;17(8):87–91. [Khaliullina MK, Gadelshina EA. The use of various bactericidal and fungicidal additives in polymers in the production of antimicrobial textile materials. Bulletin of Kazan Technological University. 2014;17(8):87–91 (in Russian).]

10. Chrusciel JJ. Modifications of Textile Materials with Functional Silanes, Liquid Silicone Softeners, and Silicone Rubbers – A Review. Polymers. 2022;14(20):4382. https://doi.org/10.3390/polym14204382

11. Сахаров КА, Андреев СВ, Зверев СА. Функциональный текстиль с антимикробными свойствами. Краткий обзор. Дезинфекционное дело. 2020;3:28–39. EDN:ywbscb. https://doi.org/10.35411/2076-457X-2020-3-28-42 [Sakharov KA, Andreev SV, Zverev SA. Antimicrobial textile finishes: a brief review. Disinfection affairs. 2020;3:28–39 (in Russian). EDN: ywbscb. https://doi.org/10.35411/2076-457X-2020-3-28-42]

12. Khashirova SYu, Musaeva YuI, Kirzhinova IKh. New nanocomposites: cotton cellulose-ketimines based on quanidine and aminoquanidine. Fibre Chemistry. 2018;50(1):60–3. https://doi.org/10.1007/s10692-018-9931-1

13. Liu J, Dong C, Wei D, Zhang Z, Xie W, Li Q, Lu Z. Multifunctional Antibacterial and Hydrophobic Cotton Fabrics Treated with Cyclic Polysiloxane Quaternary Ammonium Salt. Fibers and Polymers. 2019;20:1368–74. https://doi.org/10.1007/s12221-019-1091-2

14. Jin-Kyu K, Seung-Chan L, Song-Bae K. Synthesis of quaternary ammonium functionalized silica get through grafting of dimethyl dodecyl 3-(trimetoxysilyl) propyl ammonium chloride for nitrate removal in batch and column stadies. Journal of the Taiwan Institute of Chemical Engineers. 2019;102:153–62. https://doi.org/10.1016/j.jtice.2019.05.019

15. Han H, Liu C, Zhu J, Li FX, Wang XL, Yu JY, et al. Contact/Release Coordinated Antibacterial Cotton Fabrics Coated with N-Halamin and Cationic Antibacterial Agent for Durable Bacteria-Killing Application. International Journal of Molecular Sciences. 2020;21(24):E9489. https://doi.org/10.3390/ijms21249489

16. Ванюкова ЕА. Современные технологии получения материалов кожевенной и текстильной промышленности с антимикробными свойствами. Вестник технологического университета. 2015;18(21):58–61. [Vanukova E.A. Modern technologies for producing materials for the leather and textile industries with antimicrobial properties. Herald of Technology University. 2015;18(21):58–61 (in Russian).]

17. Ефимов КМ, Дитюк АИ, Панкратова ГП, Левчук НН, Рысина ТЗ, Богданов АИ и др. Новые полигуанидины – инновационные дезсредства пролонгированного антимикробного действия. Дезинфекционное дело. 2015;3:13–20. EDN: uibzup [Efimov KM, Dityuk AI, Pankratova GP, Levchuk NN, Rysina TZ, Bogdanov AI, Snezhko AG. New polyguanidines are innovating desinfectants with prolonged antimicrobic effect. Disinfection affairs. 2015;3:13–20 (in Russian). EDN: uibzup ]